Allergex®Tablets Uses In South Africa- Dosage, Side Effects & Safety

RxZest Medical Team

15/04/2026

ALLERGEX Tablets uses

ALLERGEX Tablets are a commonly used antihistamine medicine designed to relieve a wide range of allergy-related symptoms. They contain chlorphenamine maleate (4 mg), an active ingredient that helps reduce the body’s allergic response by blocking the effects of histamine—a chemical released during allergic reactions.

People often turn to this medicine for relief from conditions such as hay fever, skin rashes, itching, and reactions to insect bites or certain medications. While it is effective in easing discomfort, it is also known to cause drowsiness, which means it must be used responsibly and with awareness of safety precautions.

This guide provides a detailed, easy-to-understand explanation of how ALLERGEX Tablets work, who can use them, how to take them correctly, and what side effects to watch for—all written in clear South African English.

Quick facts

  • Active ingredient: Chlorphenamine maleate 4 mg
  • Medicine group: Antihistamine
  • Main purpose: Relief of allergic symptoms
  • Common effect: Drowsiness or sedation
  • Suitable for: Adults and children over 6 years
  • Not suitable for: Newborns and premature infants
  • Key caution: Avoid alcohol and driving
  • Storage: Below 30°C, away from light and moisture

What it is and what it is used for

ALLERGEX Tablets belong to a class of medicines called antihistamines. These medicines are used to treat symptoms caused by allergies, which occur when the immune system reacts to harmless substances such as pollen, dust, food, or insect stings.

Conditions treated

According to the source, ALLERGEX Tablets are used in the management of:

  • Hay fever (allergic rhinitis caused by pollen)
  • Vasomotor rhinitis (non-allergic nasal congestion)
  • Urticaria (hives or raised itchy rash)
  • Angioedema (swelling beneath the skin, often around the face or lips)
  • Allergic reactions to medications
  • Contact dermatitis (skin irritation from substances)
  • Atopic dermatitis (chronic skin condition with itching)
  • Insect bites and stings
  • General itching (pruritus)
  • Pruritus vulvae (itching in the female genital area)

These conditions can vary in severity—from mild discomfort to more serious allergic reactions—and this medicine helps control the symptoms rather than cure the underlying cause.


How it works

When your body encounters something it identifies as harmful (even if it is not), it releases histamine. This chemical is responsible for many typical allergy symptoms, including:

  • Sneezing
  • Runny or blocked nose
  • Itchy skin or eyes
  • Swelling
  • Redness

Chlorphenamine blocks histamine receptors in the body. By doing so, it prevents histamine from triggering these symptoms. This helps reduce inflammation, itching, and other discomforts associated with allergies.

However, because histamine also plays a role in keeping you alert, blocking it can lead to drowsiness. That is why this medicine may make you feel sleepy.


Who should NOT use this medicine

It is important to know when this medicine should be avoided.

Do not take ALLERGEX Tablets if:

  • You are allergic to chlorphenamine maleate or any of the ingredients
  • You have epilepsy or a history of repeated seizures
  • You are experiencing an acute asthma attack
  • You are a premature infant or a newborn baby

Warning: Taking this medicine when it is not suitable for you may increase the risk of serious side effects.


Warnings and precautions (Read before use)

Before starting ALLERGEX Tablets, consider the following safety information.

Drowsiness and alertness

  • This medicine commonly causes sleepiness
  • It may slow your reaction time
  • Avoid driving, cycling, or operating machinery

Alcohol and sedatives

  • Alcohol can increase the sedative effects
  • Combining with sleeping tablets or tranquillisers can worsen drowsiness

Medical conditions requiring caution

Speak to a healthcare professional before use if you have:

  • Enlarged prostate
  • Glaucoma
  • Urinary retention

Skin testing

  • The medicine may interfere with allergy skin tests
  • It should be stopped before testing

Pregnancy, planning pregnancy, and breastfeeding

  • The safety of ALLERGEX Tablets during pregnancy and breastfeeding has not been established
  • You should consult a doctor or pharmacist before use
  • This applies if you are pregnant, planning pregnancy, or breastfeeding

Interactions

Some medicines may interact with ALLERGEX Tablets, affecting how they work or increasing side effects.

Known interactions

  • CNS depressants (e.g. sleeping tablets, tranquillisers)
  • Phenytoin (used for epilepsy)
  • Monoamine oxidase inhibitors (MAOIs)
  • Medicines for Parkinson’s disease

Practical tips

  • Always inform your healthcare provider about all medicines you take
  • Include herbal and traditional remedies
  • Avoid alcohol while using this medicine

How to take (Step-by-step)

Follow these steps carefully:

  1. Take exactly as directed by your doctor or pharmacist
  2. Swallow the tablet with water
  3. Take doses at evenly spaced intervals
  4. Do not exceed the recommended daily dose
  5. Do not share your medicine with others

Missed dose

  • Take it when you remember
  • Skip if your next dose is near
  • Do not take two doses at once

Overdose

Taking too much can be dangerous.

Symptoms may include:

  • Hallucinations or confusion
  • Tremors or seizures
  • Severe drowsiness or coma
  • Dry mouth and flushed skin
  • High temperature
  • Breathing or heart complications

Action: Seek immediate medical help.


Dosing table

Age GroupDoseFrequencyMaximum per 24 hours
Adults & children (12+)4 mgEvery 4–6 hours24 mg
Children (6–12 years)2 mgEvery 4–6 hours12 mg
Children under 6Not recommendedNot recommendedNot recommended

Possible side effects

Common side effects

  • Drowsiness
  • Dizziness
  • Headache
  • Blurred vision
  • Nausea or vomiting
  • Diarrhoea
  • Dry mouth
  • Constipation
  • Appetite changes
  • Muscle weakness or tremors

Less common

Not specified in the source.

Serious — seek urgent help

  • Swelling of the face, lips, or throat
  • Difficulty breathing
  • Irregular heartbeat
  • Yellowing of the skin or eyes
  • Severe dizziness or fainting

Storage and disposal

Storage

  • Store below 30°C
  • Keep in a tightly closed container
  • Protect from light
  • Keep out of reach of children

Disposal

  • Return unused medicine to a pharmacist
  • Do not dispose in water systems

What the medicine contains

  • Chlorphenamine maleate 4 mg
  • Lactose 119.80 mg

Pack information and appearance

Appearance

  • Yellow, round tablets
  • Convex shape
  • Scored on one side
  • Marked with “A” on the other side

Packaging

  • Packs of 30 and 100
  • Bulk packs of 1,000
  • Available in blister packs or containers

Practical FAQs

Can I drink alcohol?

No. It increases drowsiness.

Can I drive?

No. It affects alertness.

Can children take it?

Yes, if over 6 years.

What if I miss a dose?

Take it when remembered unless near next dose.

Is it safe in pregnancy?

Not established—consult a doctor.


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