SCHEDULING STATUS
S3
Product Name
RIDAQ-12,5 tablet
Active Ingredient
Hydrochlorothiazide
Sugar Information
RIDAQ-12,5 contains sugar: Lactose monohydrate 62,6 mg.
Read Before Taking RIDAQ-12,5
Read this information carefully before you start taking RIDAQ-12,5.
Keep this information because you may need to read it again. If you have further questions, ask your doctor, pharmacist, nurse or other healthcare provider.
RIDAQ-12,5 has been prescribed for you personally and should not be shared with other people. It may harm them, even if their symptoms are the same as yours.
What Is in This Article
- What RIDAQ-12,5 is and what it is used for
- What you need to know before you take RIDAQ-12,5
- How to take RIDAQ-12,5
- Possible side effects
- How to store RIDAQ-12,5
- Contents of the pack and other information
1. What RIDAQ-12,5 Is and What It Is Used For
RIDAQ-12,5 is a water tablet used for mild to moderate high blood pressure alone or in combination with other anti-high blood pressure medicines.
2. What You Need to Know Before You Take RIDAQ-12,5
Do Not Take RIDAQ-12,5
Do not take RIDAQ-12,5 if any of the following apply:
| Do not take RIDAQ-12,5 if | Details |
|---|---|
| You are allergic to hydrochlorothiazide | This includes hypersensitivity to the active substance |
| You are allergic to other medicines containing sulphonamides | This may increase the risk of allergic reaction |
| You are allergic to any other ingredient in RIDAQ-12,5 | See the contents section |
| You have severe kidney problems | RIDAQ-12,5 should not be used |
| You have severe liver problems | RIDAQ-12,5 should not be used |
| You have Addison’s disease | This is when the adrenal glands produce too little cortisol and often too little aldosterone |
| You have an increased amount of calcium in your blood | RIDAQ-12,5 should not be used |
| You previously had or currently have cancer of the skin and/or lip | RIDAQ-12,5 should not be used |
| You are in the second or third trimester of pregnancy | RIDAQ-12,5 should not be used |
| You are breastfeeding | RIDAQ-12,5 should not be used |
Warnings and Precautions
Take Special Care With RIDAQ-12,5
Take special care with RIDAQ-12,5 if any of the following apply:
| Situation requiring special care | Details |
|---|---|
| You have high blood sugar | RIDAQ-12,5 may increase blood sugar and aggravate or unmask diabetes mellitus |
| You take medicine to treat diabetes | Blood sugar concentrations should be monitored |
| You experience dry mouth, thirst, weakness, tiredness, drowsiness, restlessness, confusion, fits, muscle pains, cramps or weakness, low blood pressure, reduced urine, fast irregular heartbeat, nausea or vomiting | These may be signs of fluid and electrolyte imbalance |
| You are vomiting or receiving intravenous fluid therapy | Careful observation for fluid and electrolyte imbalance may be needed |
| You are elderly | Elderly patients may be more prone to electrolyte imbalances |
| You are taking corticosteroids, ACTH or corticotropin | These may increase the risk of low potassium levels |
| You have been taking RIDAQ-12,5 for a long time | Long-term use may cause low potassium levels |
| You are taking digoxin | Low potassium may affect the way your heart beats and may worsen digoxin-related heart rhythm problems |
| You experience extreme fatigue, muscle weakness, breathing problems and excessive thirst | These may be signs of chloride deficiency |
| You retain water, especially in hot weather | RIDAQ-12,5 may cause a decrease in blood sodium |
| You suffer from gout | RIDAQ-12,5 may cause a gout attack |
| You have low magnesium levels | RIDAQ-12,5 may increase magnesium excretion through urine |
| You have high calcium levels | RIDAQ-12,5 may decrease calcium excretion through urine and increase calcium in the body |
| You are going to have a parathyroid function test | RIDAQ-12,5 should be discontinued before the test |
| You have high cholesterol or high triglyceride levels | RIDAQ-12,5 may increase these levels |
| You have systemic lupus erythematosus | RIDAQ-12,5 may exacerbate or activate this condition |
| You are taking medicines for high blood pressure | Medical monitoring may be needed |
| You have a history of allergy or asthma | RIDAQ-12,5 may cause allergic reactions |
| You are taking lithium | Lithium is used to treat mental disorders |
| You experience decreased vision and eye pain | Stop taking RIDAQ-12,5 and contact your doctor immediately |
| You have a history of sulphonamide medicine or penicillin antibiotic allergy | You may be at higher risk of certain eye reactions |
| You had surgery to stop excessive sweating | This is called sympathectomy |
| You are going to have an anti-doping test | RIDAQ-12,5 could show a false positive result |
| You have had skin cancer or develop an unexpected skin lesion | Long-term use with high doses may increase the risk of some types of skin and lip cancer |
| You are exposed to sun or UV rays | Protect your skin while taking RIDAQ-12,5 |
| You experience decrease in vision or eye pain | These may be symptoms of choroidal effusion or acute angle-closure glaucoma |
Decreased vision or eye pain may be caused by fluid accumulation in the vascular layer of the eye or an increase in pressure in the eye. This can happen when taking RIDAQ-12,5 and may lead to permanent vision loss if not treated.
Children
The safety and effectiveness of RIDAQ-12,5 have not been established in children.
Other Medicines and RIDAQ-12,5
Always tell your healthcare provider if you are taking any other medicines, including complementary or traditional medicines.
Tell your doctor if you are taking any of the following medicines:
| Medicine or medicine group | Use or concern |
|---|---|
| Amphotericin B, parenteral | Used to treat fungal infections |
| Carbenoxolone | Used to treat stomach ulcers |
| Stimulant laxatives | Used to treat constipation |
| Digitalis glycosides, such as digoxin | Used to increase heart contractions |
| Antidiabetic medicines, including insulin and oral antidiabetics | Used to treat high blood sugar caused by diabetes mellitus |
| Calcium salts | Used to treat calcium deficiency |
| Colestyramine resin and colestipol | Used to treat high cholesterol |
| Tubocurarine | Used as a muscle relaxant |
| Antihypertensive medicines | Used to treat high blood pressure |
| Alcohol | RIDAQ-12,5 may interact with alcohol |
| Barbiturates | Used to calm you or induce sleep |
| Opioids | Used to treat pain |
| Corticosteroids | Used as anti-inflammatory medicine and to prevent immune response |
| ACTH or corticotropin | Used for adrenal gland testing or to treat certain conditions |
| Beta2-agonists such as salbutamol | Used to treat asthma |
| Noradrenaline | Used to treat low blood pressure in specific situations |
| Lithium | Used to treat mental disorders |
| Non-steroidal anti-inflammatory drugs, also called NSAIDs | Used to treat pain, fever, blood clots and inflammation |
| Anti-dysrhythmics | Used to treat heart rhythm disorders |
| Antipsychotics | Used to treat mental disorders |
| Laboratory tests for parathyroid function | RIDAQ-12,5 may affect test interpretation |
| Laboratory tests for pancreas function | RIDAQ-12,5 may affect test interpretation |
RIDAQ-12,5 With Food and Drink
RIDAQ-12,5 should be taken with or after meals to minimise stomach upset.
Alcohol should be avoided.
Pregnancy, Breastfeeding and Fertility
You should not take RIDAQ-12,5 if you are pregnant or breastfeeding your baby.
If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, consult your doctor, pharmacist or other healthcare provider for advice before taking this medicine.
Driving and Using Machines
RIDAQ-12,5 has moderate influence on the ability to drive and use machines.
Since adverse reactions such as tiredness, dizziness and blurred vision have been reported, do not drive, use machinery or perform tasks that require concentration until you are certain that RIDAQ-12,5 does not adversely affect your ability to do so.
RIDAQ-12,5 Contains Lactose
If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking RIDAQ-12,5.
3. How to Take RIDAQ-12,5
Do not share medicines prescribed for you with any other person.
Always take RIDAQ-12,5 exactly as your doctor has instructed you.
Usual Dose
| Use | Dose |
|---|---|
| High blood pressure in adults | One tablet daily |
| Additional medicine in the treatment of high blood pressure in adults | One to two tablets daily with an anti-hypertensive medicine |
The dosage should not be higher than needed to reach the desired effect.
Long-term treatment may cause a decrease in electrolytes known as potassium ions. You may need to take potassium supplements.
If a single dose is indicated, RIDAQ-12,5 should preferably be taken in the morning to minimise increased urination during sleep.
If the effect of RIDAQ-12,5 seems too strong or too weak, tell your doctor or pharmacist.
If You Take More RIDAQ-12,5 Than You Should
In the event of overdosage, consult your doctor or pharmacist.
If neither is available, contact the nearest hospital or poison control centre.
If You Forget to Take RIDAQ-12,5
Do not take a double dose to make up for forgotten individual doses.
4. Possible Side Effects
RIDAQ-12,5 can have side effects.
Not all side effects reported for RIDAQ-12,5 are included here. If your general health worsens or if you experience any untoward effects while taking RIDAQ-12,5, consult your healthcare provider for advice.
Side Effects Table
| Side-effect category | Side effects / symptoms | Recommended action |
|---|---|---|
| Very serious allergic reactions | Swelling of the hands, feet, ankles, face, lips, mouth or throat, which may cause difficulty swallowing or breathing | Stop taking RIDAQ-12,5 and seek urgent medical attention immediately |
| Very serious allergic reactions | Rash or itching | Stop taking RIDAQ-12,5 and seek urgent medical attention immediately |
| Very serious skin reactions | Blistering of the skin, mouth, eyes and genitals, which may be due to Stevens-Johnson Syndrome | Stop taking RIDAQ-12,5 and seek urgent medical attention immediately |
| Very serious skin reactions | Fever, flu-like symptoms, painful red rash, possible purplish spots, rash spreading, blistering, skin death and peeling, known as toxic epidermal necrolysis | Stop taking RIDAQ-12,5 and seek urgent medical attention immediately |
| Serious side effects | Abnormal or irregular heart rhythm, muscle weakness and twitching that could be caused by low potassium levels | Tell your doctor immediately or go to the nearest casualty department |
| Serious side effects | Seizures or fits | Tell your doctor immediately or go to the nearest casualty department |
| Serious side effects | Sore or ulcer on the lining of the food pipe, stomach or small intestine, with symptoms such as upper abdominal pain | Tell your doctor immediately |
| Serious side effects | Yellow pigmentation of skin and eyes caused by liver or blood problems, also called jaundice | Tell your doctor immediately |
| Serious side effects | Inflammation of the pancreas causing severe pain in the abdomen and back | Tell your doctor immediately |
| Serious side effects | Serious decrease of blood cells causing weakness, bruising or making infections more likely | Tell your doctor immediately |
| Serious side effects | Excessive fluid accumulation in lungs | Tell your doctor immediately |
| Serious side effects | Kidney failure, swelling and inflammation between the kidney tubules | Tell your doctor immediately |
| Serious side effects | Too few white blood cells, known as neutropenia | Tell your doctor immediately |
| Serious side effects | Inflammation of the lungs causing breathlessness, cough and raised temperature, or difficulty breathing | Tell your doctor immediately |
| Serious side effects | Skin cancer signs such as a sore that does not heal or returns after healing, scar-like pale white or yellow flat areas, raised scaly red patches, pearly white, pink or red shiny lumps, or pink growths with raised edges and indents in the centre | Tell your doctor immediately |
| Frequent side effects | Electrolyte imbalances | Tell your doctor |
| Frequent side effects | Decrease in chloride in the blood | Tell your doctor |
| Frequent side effects | Low sodium levels causing tiredness and confusion, muscle twitching, fits or coma | Tell your doctor immediately |
| Frequent side effects | Stomach and intestine complaints | Tell your doctor if troublesome |
| Frequent side effects | Dry mouth | Tell your doctor if troublesome |
| Frequent side effects | Thirst and weakness | Tell your doctor |
| Frequent side effects | Mental and physical sluggishness or drowsiness | Tell your doctor |
| Frequent side effects | Restlessness | Tell your doctor |
| Frequent side effects | Muscle pain and cramps | Tell your doctor |
| Frequent side effects | Reduced urine production | Tell your doctor |
| Less frequent side effects | Metabolic disturbances, especially at high doses | Tell your doctor |
| Less frequent side effects | High blood sugar and glucose in the urine in diabetic and susceptible patients | Tell your doctor |
| Less frequent side effects | Increased uric acid levels causing gout attacks in some patients | Tell your doctor |
| Less frequent side effects | Reduced urinary excretion of calcium | Tell your doctor |
| Less frequent side effects | Deficiency of magnesium in the blood | Tell your doctor |
| Less frequent side effects | Harmful changes in plasma lipids | Tell your doctor |
| Less frequent side effects | Loss of appetite, stomach irritation, nausea, vomiting, constipation or diarrhoea | Tell your doctor if troublesome |
| Less frequent side effects | Headache or dizziness | Tell your doctor |
| Less frequent side effects | Increased sensitivity of skin to sun | Protect skin from sunlight and tell your doctor |
| Less frequent side effects | Numbness, tingling, pins and needles, cold, warmth or pressure sensations of the skin | Tell your doctor |
| Less frequent side effects | Fall in blood pressure on standing up, causing dizziness or fainting | Tell your doctor |
| Less frequent side effects | Yellow vision | Tell your doctor |
| Less frequent side effects | Inflammation of a salivary gland | Tell your doctor |
| Less frequent side effects | Sense of spinning, also called vertigo | Tell your doctor |
| Less frequent side effects | Loss of male sexual ability | Tell your doctor |
| Side effects with unknown frequency | Fever | Tell your doctor |
| Side effects with unknown frequency | Light-headedness | Tell your doctor |
| Side effects with unknown frequency | Feelings of sadness or worthlessness, also called depression, or sleep disturbances | Tell your doctor |
| Side effects with unknown frequency | Muscle spasm | Tell your doctor |
| Side effects with unknown frequency | Kidney problems | Tell your doctor |
| Side effects with unknown frequency | Temporary blurred vision | Tell your doctor |
| Side effects with unknown frequency | Hair loss | Tell your doctor |
| Side effects with unknown frequency | Increased blood levels of cholesterol and triglycerides | Tell your doctor |
| Side effects with unknown frequency | Inflammation of blood vessel walls, often with skin rash or inflamed blood vessels in the skin | Tell your doctor |
| Side effects with unknown frequency | Small purple-coloured spots caused by bleeding into the skin | Tell your doctor |
| Side effects with unknown frequency | Decrease in vision or eye pain due to high pressure, possible choroidal effusion or acute angle-closure glaucoma | Stop taking RIDAQ-12,5 and contact your doctor immediately |
| Side effects not listed | Any side effect not mentioned or any unexpected health change | Inform your doctor or pharmacist |
Reporting of Side Effects
If side effects occur, talk to your doctor, pharmacist or nurse.
Reporting side effects helps provide more information on the safety of RIDAQ-12,5.
5. How to Store RIDAQ-12,5
Store all medicines out of reach of children.
Store at or below 25 °C.
Store in a well-closed container.
Protect from light and moisture.
Do not store in a bathroom.
Do not use after the expiry date stated on the label.
Return all unused medicine to your pharmacist.
Do not dispose of unused medicine in drains or sewerage systems, including toilets.
6. Contents of the Pack and Other Information
What RIDAQ-12,5 Contains
The active substance is 12,5 mg hydrochlorothiazide.
The other ingredients are:
| Other ingredients |
|---|
| Lactose monohydrate |
| Magnesium stearate |
| Maize starch |
| Microcrystalline cellulose PH 101 |
| Polysorbate 80 |
| Purified talc |
| Sodium starch glycolate, Type A |
Contains sugar: Lactose monohydrate 62,6 mg.
What RIDAQ-12,5 Looks Like and Contents of the Pack
RIDAQ-12,5 is a round, white tablet, flat with bevelled edges, bisected on one side.
RIDAQ-12,5 is available in the following packaging:
| Packaging type | Pack details |
|---|---|
| Metallised layflat bags | Silver metallised layflat “bank bag” sealed with a perforated tear line; each bag contains 28 tablets |
| HDPE bottle | White 60 mL high-density polyethylene bottle with rayon insert, sealing foil and white polypropylene cap; each bottle contains 30 tablets |
| Securitainers | White polypropylene securitainer with foam insert and tamper-evident closure; each securitainer contains 500 tablets |
| Blisters | PVC or PVC/PVDC blister packs of 28 and 30 tablets, packed in a cardboard carton |
Not all packs and pack sizes are necessarily marketed.
Holder of Certificate of Registration
PHARMACARE LIMITED
Healthcare Park
Woodlands Drive
Woodmead 2191
Hotline: 0800 122 912
This Leaflet Was Last Revised In
04 March 2023
Registration Number
A39/18.1/0399
Access to the Corresponding Professional Information
Professional information and patient information leaflets are available through the SAHPRA repository and Aspen Pharmacare medical information channels.
Medical Disclaimer
This article is intended as patient information based on the approved leaflet structure. It does not replace advice from a doctor, pharmacist, nurse or other healthcare provider. For regulated medical product use, follow the approved patient information leaflet and healthcare professional guidance.
