{"id":951,"date":"2026-04-23T11:48:04","date_gmt":"2026-04-23T11:48:04","guid":{"rendered":"https:\/\/rxzest.com\/en-za\/?p=951"},"modified":"2026-05-13T11:12:38","modified_gmt":"2026-05-13T11:12:38","slug":"sinuend-tablets-africa-dosage-side-effects","status":"publish","type":"post","link":"https:\/\/rxzest.com\/en-za\/sinuend-tablets-africa-dosage-side-effects\/","title":{"rendered":"Sinuend tablets in South Africa: Uses, Dosage, Side Effects"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">If you are using <strong>Sinuend tablets<\/strong>, this medicine is meant to help with the symptoms that often come with a cold or flu. It is used for <strong>blocked nose (nasal congestion)<\/strong> as well as <strong>minor aches and pains<\/strong> linked to colds and influenza. In South Africa, it is listed as a <strong>Schedule 2 (S2)<\/strong> medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What it is and what it is used for<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Sinuend is a <strong>tablet medicine for cold and flu symptoms<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading has-medium-font-size\">Active ingredients<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Each tablet contains:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Paracetamol 200 mg<\/strong><\/li>\n\n\n\n<li><strong>Ephedrine hydrochloride 6 mg<\/strong><\/li>\n\n\n\n<li><strong>Caffeine 20 mg<\/strong><\/li>\n\n\n\n<li><strong>Chlorpheniramine maleate 2 mg<\/strong><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">What type of medicine it is<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The source describes Sinuend as a preparation for the common cold that includes a <strong>nasal decongestant<\/strong> and an <strong>antihistamine<\/strong>. It also has <strong>analgesic<\/strong> (pain-relieving), <strong>antipyretic<\/strong> (fever-reducing), <strong>sympathomimetic<\/strong> (decongestant-type), and <strong>antihistaminic<\/strong> properties.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What it is used for<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">You may use Sinuend for the <strong>symptomatic relief<\/strong> of symptoms linked to <strong>colds and influenza<\/strong>, including:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Nasal congestion<\/strong><\/li>\n\n\n\n<li><strong>Minor aches and pains<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">This means it helps relieve symptoms, but the source does <strong>not<\/strong> say that it treats the cause of the infection itself.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How it works (simple explanation)<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Sinuend combines four medicines that work in different ways.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Paracetamol<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Paracetamol helps to ease <strong>pain<\/strong> and reduce <strong>fever<\/strong>. If you have body aches, headache, or feel feverish with a cold or flu, this ingredient is the part that helps with those symptoms.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Ephedrine hydrochloride<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Ephedrine hydrochloride acts as a <strong>decongestant<\/strong>. In simple terms, it helps open the nose when you are feeling blocked up. This can make breathing through your nose easier when you have a cold or flu.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Chlorpheniramine maleate<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Chlorpheniramine maleate is an <strong>antihistamine<\/strong>. This means it helps with symptoms linked to the body\u2019s histamine response. The source includes it as part of the medicine\u2019s antihistaminic effect.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Caffeine<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Caffeine is also included in the tablet. The source identifies it as one of the active ingredients and notes that it can affect the stomach and central nervous system.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Because the tablet combines these ingredients, it is designed to help more than one cold or flu symptom at the same time.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Who should NOT use this medicine<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Do <strong>not<\/strong> use Sinuend if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Are <strong>allergic or hypersensitive<\/strong> to any of its ingredients<\/li>\n\n\n\n<li>Have <strong>severe liver impairment<\/strong><\/li>\n\n\n\n<li>Have <strong>severe kidney impairment<\/strong><\/li>\n\n\n\n<li>Have <strong>cardiovascular disease<\/strong><\/li>\n\n\n\n<li>Have <strong>kidney disease<\/strong><\/li>\n\n\n\n<li>Have <strong>high blood pressure (hypertension)<\/strong><\/li>\n\n\n\n<li>Have an <strong>overactive thyroid (hyper-thyroidism)<\/strong><\/li>\n\n\n\n<li>Have <strong>hyperexcitability<\/strong><\/li>\n\n\n\n<li>Have <strong>phaeochromocytoma<\/strong><\/li>\n\n\n\n<li>Have <strong>closed-angle glaucoma<\/strong><\/li>\n\n\n\n<li>Have <strong>prostatism<\/strong><\/li>\n\n\n\n<li>Have <strong>bladder dysfunction<\/strong><\/li>\n\n\n\n<li>Are being treated with <strong>monoamine oxidase inhibitors (MAOIs)<\/strong><\/li>\n\n\n\n<li>Have taken an MAOI within the <strong>last 14 days<\/strong><\/li>\n\n\n\n<li>Have <strong>epilepsy<\/strong><\/li>\n\n\n\n<li>Have <strong>any convulsive disorder<\/strong><\/li>\n\n\n\n<li>Are currently having an <strong>asthma attack<\/strong><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Important note<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">If any of the conditions above apply to you, do not start this medicine unless a doctor specifically advises you to do so.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and precautions (Read before use)<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Before using Sinuend, there are some important safety points to keep in mind.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Do not take more than the recommended dose<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Taking more than the recommended amount can cause <strong>severe liver damage<\/strong>. This is especially important because paracetamol is one of the ingredients.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">If you have liver or kidney disease<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">If you have <strong>liver disease<\/strong> or <strong>kidney disease<\/strong>, the source says paracetamol should be taken <strong>under medical supervision<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">If your symptoms do not improve<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">If you do not get relief when using the recommended dose, you should <strong>consult your doctor<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Do not use it for too long without medical advice<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Do <strong>not<\/strong> use Sinuend continuously for <strong>more than 10 days<\/strong> unless your doctor tells you to.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Drowsiness and impaired concentration<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">This medicine may cause:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Drowsiness<\/strong><\/li>\n\n\n\n<li><strong>Poor concentration<\/strong><\/li>\n\n\n\n<li><strong>Impaired decision-making<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">This effect may become worse if you take it with <strong>alcohol<\/strong> or other medicines that depress the central nervous system.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Warning:<\/strong> Do <strong>not<\/strong> drive, operate dangerous machinery, or climb dangerous heights if this medicine affects your alertness. The source specifically warns that impaired judgement could lead to accidents.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Heart-related caution<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Ephedrine hydrochloride should be used with caution if you have:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Organic heart disease<\/strong><\/li>\n\n\n\n<li><strong>Cardiac decompensation<\/strong><\/li>\n\n\n\n<li><strong>Angina of effort<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">The source also states that <strong>anginal pain may be triggered<\/strong> in people with <strong>angina pectoris<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Anaesthesia warning<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Sinuend should be <strong>avoided during anaesthesia<\/strong> with:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Cyclopropane<\/strong><\/li>\n\n\n\n<li><strong>Halothane<\/strong><\/li>\n\n\n\n<li>Other <strong>halogenated anaesthetics<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">If you are going for an operation or procedure, tell the doctor or anaesthetist that you are taking this medicine.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Caffeine-related caution<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Caffeine should be used with caution if you have a history of:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Peptic ulceration<\/strong><\/li>\n\n\n\n<li><strong>Hyperacidity<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">The source also says that long-term high intake of caffeine may lead to:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Tolerance<\/strong> to some effects<\/li>\n\n\n\n<li><strong>Physical withdrawal signs<\/strong> if stopped suddenly<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Older adults<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Older adults may be especially sensitive to the effects of chlorpheniramine, including:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Antimuscarinic effects<\/strong><\/li>\n\n\n\n<li><strong>Sedation<\/strong><\/li>\n\n\n\n<li><strong>Low blood pressure (hypotension)<\/strong><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, planning pregnancy, and breastfeeding<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The source says that the <strong>safe use of Sinuend in pregnancy and lactation has not been established<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If you are:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Pregnant<\/li>\n\n\n\n<li>Planning a pregnancy<\/li>\n\n\n\n<li>Breastfeeding<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">speak to your <strong>doctor or pharmacist before use<\/strong>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Interactions<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Sinuend can interact with other medicines.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Medicines that may increase the risk of heart rhythm problems<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">There may be an increased risk of <strong>arrhythmias<\/strong> if Sinuend is taken with:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Cardiac glycosides<\/strong><\/li>\n\n\n\n<li><strong>Quinidine<\/strong><\/li>\n\n\n\n<li><strong>Tricyclic antidepressants<\/strong><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Medicines and substances that may make drowsiness worse<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Chlorpheniramine maleate may increase the sedative effect of:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Alcohol<\/strong><\/li>\n\n\n\n<li><strong>Barbiturates<\/strong><\/li>\n\n\n\n<li><strong>Hypnotics<\/strong><\/li>\n\n\n\n<li><strong>Opioid analgesics<\/strong><\/li>\n\n\n\n<li><strong>Anxiolytic sedatives<\/strong><\/li>\n\n\n\n<li><strong>Neuroleptics<\/strong><\/li>\n\n\n\n<li>Other <strong>central nervous system depressants<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Note:<\/strong> If you are taking any medicine that makes you sleepy, check with a healthcare professional before using Sinuend.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">MAOIs<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">MAOIs may increase the <strong>antimuscarinic effects<\/strong> of antihistamines.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This is one reason why Sinuend must not be used if you are on an MAOI or if you stopped it within the last 14 days.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Other antimuscarinic medicines<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The effects of antimuscarinic medicines such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Atropine<\/strong><\/li>\n\n\n\n<li><strong>Tricyclic antidepressants<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">may also be enhanced.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Food, alcohol, and tests<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Alcohol:<\/strong> The source specifically warns that alcohol can worsen drowsiness and impaired concentration.<\/li>\n\n\n\n<li><strong>Food:<\/strong> Not specified in the source.<\/li>\n\n\n\n<li><strong>Medical tests:<\/strong> Not specified in the source.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to take (Step-by-step)<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Always use Sinuend exactly as described in the source.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Usual adult dose<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Adults:<\/strong> Take <strong>2 tablets every 4 hours<\/strong>.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Dose for children<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Children 8 to 12 years:<\/strong> Take <strong>1 tablet every 4 hours<\/strong>.<\/li>\n\n\n\n<li><strong>Children under 8 years:<\/strong> <strong>Not recommended<\/strong>.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">When to take it<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The source gives the dose interval as <strong>every 4 hours<\/strong>. It does <strong>not<\/strong> say whether to take it with food or on an empty stomach.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>With food: <strong>Not specified in the source<\/strong><\/li>\n\n\n\n<li>Without food: <strong>Not specified in the source<\/strong><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Practical steps to help you take it correctly<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Check the <strong>time<\/strong> of your last dose before taking more.<\/li>\n\n\n\n<li>Keep to the <strong>4-hour interval<\/strong>.<\/li>\n\n\n\n<li>Do not continue beyond <strong>10 days<\/strong> without medical advice.<\/li>\n\n\n\n<li>If you are also using any other medicine for pain, flu, or a blocked nose, check the ingredients first, especially for <strong>paracetamol<\/strong>. The source warns that taking too much can cause severe liver damage.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Missed dose<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Not specified in the source.<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Overdose<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">If too much is taken, this is a <strong>medical emergency<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The source says:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Consult a doctor immediately<\/strong>, or<\/li>\n\n\n\n<li><strong>Take the patient to the nearest hospital immediately<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Specialised treatment is needed as soon as possible. The source also says that the latest information on overdose treatment can be obtained from the <strong>nearest poison centre<\/strong>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Dosing table<\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><th>Age group<\/th><th class=\"has-text-align-right\" data-align=\"right\">Dose<\/th><th>Frequency<\/th><th>Maximum daily dose<\/th><\/tr><\/thead><tbody><tr><td>Adults<\/td><td class=\"has-text-align-right\" data-align=\"right\">2 tablets<\/td><td>Every 4 hours<\/td><td>Not specified in the source<\/td><\/tr><tr><td>Children 8 to 12 years<\/td><td class=\"has-text-align-right\" data-align=\"right\">1 tablet<\/td><td>Every 4 hours<\/td><td>Not specified in the source<\/td><\/tr><tr><td>Children under 8 years<\/td><td class=\"has-text-align-right\" data-align=\"right\">Not recommended<\/td><td>Not applicable<\/td><td>Not applicable<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Not everyone gets side effects, but it is important to know what may happen.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Common<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The source states that the following may occur:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Headache<\/strong><\/li>\n\n\n\n<li><strong>Sedation or drowsiness<\/strong><\/li>\n\n\n\n<li><strong>Difficulty concentrating<\/strong><\/li>\n\n\n\n<li><strong>Tiredness (lassitude)<\/strong><\/li>\n\n\n\n<li><strong>Poor co-ordination<\/strong><\/li>\n\n\n\n<li><strong>Nausea<\/strong><\/li>\n\n\n\n<li><strong>Vomiting<\/strong><\/li>\n\n\n\n<li><strong>Diarrhoea<\/strong><\/li>\n\n\n\n<li><strong>Epigastric pain<\/strong> (pain in the upper stomach area)<\/li>\n\n\n\n<li><strong>Dry mouth<\/strong><\/li>\n\n\n\n<li><strong>Constipation<\/strong><\/li>\n\n\n\n<li><strong>Blurred vision<\/strong><\/li>\n\n\n\n<li><strong>Difficulty passing urine<\/strong><\/li>\n\n\n\n<li><strong>Urinary retention<\/strong><\/li>\n\n\n\n<li><strong>Sweating<\/strong><\/li>\n\n\n\n<li><strong>Restlessness<\/strong><\/li>\n\n\n\n<li><strong>Tremor<\/strong><\/li>\n\n\n\n<li><strong>Insomnia<\/strong><\/li>\n\n\n\n<li><strong>Reduced appetite<\/strong><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Less common<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The source says these can occur occasionally or may occur:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Skin rashes<\/strong><\/li>\n\n\n\n<li><strong>Other allergic reactions<\/strong><\/li>\n\n\n\n<li><strong>Pancreatitis<\/strong><\/li>\n\n\n\n<li><strong>Confusion<\/strong><\/li>\n\n\n\n<li><strong>Irritability<\/strong><\/li>\n\n\n\n<li><strong>Weakness<\/strong><\/li>\n\n\n\n<li><strong>Dyspnoea<\/strong> (shortness of breath)<\/li>\n\n\n\n<li><strong>Hypersalivation<\/strong><\/li>\n\n\n\n<li><strong>Tightness of the chest<\/strong><\/li>\n\n\n\n<li><strong>Thickened respiratory secretions<\/strong><\/li>\n\n\n\n<li><strong>Increased gastric reflux<\/strong><\/li>\n\n\n\n<li><strong>Changes in glucose metabolism<\/strong><\/li>\n\n\n\n<li><strong>Paradoxical stimulation<\/strong>, especially in children, such as nervousness, euphoria, tremors, or insomnia<\/li>\n\n\n\n<li><strong>Extrapyramidal symptoms<\/strong> (movement-related side effects)<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Serious\u2014seek urgent help<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Get urgent medical help if you notice symptoms such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Allergic reactions<\/strong><\/li>\n\n\n\n<li><strong>Very severe drowsiness<\/strong><\/li>\n\n\n\n<li><strong>Hallucinations<\/strong><\/li>\n\n\n\n<li><strong>Convulsions<\/strong><\/li>\n\n\n\n<li><strong>Psychotic states<\/strong><\/li>\n\n\n\n<li><strong>Palpitations<\/strong><\/li>\n\n\n\n<li><strong>Arrhythmias<\/strong><\/li>\n\n\n\n<li><strong>Marked urinary retention<\/strong><\/li>\n\n\n\n<li><strong>Severe breathing difficulty<\/strong><\/li>\n\n\n\n<li><strong>Blood-related reactions<\/strong> such as thrombocytopenia, leucopenia, pancytopenia, neutropenia, or agranulocytosis<\/li>\n\n\n\n<li><strong>Severe stomach symptoms or ongoing vomiting<\/strong><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">What to do if side effects happen<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>If you feel <strong>sleepy or dizzy<\/strong>, avoid driving or any risky activity.<\/li>\n\n\n\n<li>If side effects are severe, unusual, or worrying, seek medical advice.<\/li>\n\n\n\n<li>If you think you or someone else has taken too much, go to the <strong>nearest hospital immediately<\/strong>.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Storage and disposal<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">How to store Sinuend<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Store at or below <strong>25 \u00b0C<\/strong><\/li>\n\n\n\n<li>Protect it from <strong>light<\/strong><\/li>\n\n\n\n<li>Protect it from <strong>moisture<\/strong><\/li>\n\n\n\n<li>Keep it <strong>out of reach of children<\/strong><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Expiry<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Expiry guidance is <strong>not specified in the source<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Disposal<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Disposal instructions are <strong>not specified in the source<\/strong>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine contains<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Active ingredients<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Each tablet contains:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Paracetamol 200 mg<\/strong><\/li>\n\n\n\n<li><strong>Ephedrine hydrochloride 6 mg<\/strong><\/li>\n\n\n\n<li><strong>Caffeine 20 mg<\/strong><\/li>\n\n\n\n<li><strong>Chlorpheniramine maleate 2 mg<\/strong><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Other ingredients<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The source lists these excipients:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Maize starch<\/strong><\/li>\n\n\n\n<li><strong>Lactose<\/strong><\/li>\n\n\n\n<li><strong>Gelatin<\/strong><\/li>\n\n\n\n<li><strong>Carmoisine Red (CI 14720)<\/strong><\/li>\n\n\n\n<li><strong>Green \u2018S\u2019 (CI 44090)<\/strong><\/li>\n\n\n\n<li><strong>Magnesium stearate<\/strong><\/li>\n\n\n\n<li><strong>Talc<\/strong><\/li>\n\n\n\n<li><strong>Sodium starch glycollate<\/strong><\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Note:<\/strong> This product <strong>contains lactose<\/strong>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pack information and appearance<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">What the tablets look like<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Sinuend tablets are described as:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Red and blue mottled<\/strong><\/li>\n\n\n\n<li><strong>Round<\/strong><\/li>\n\n\n\n<li><strong>Biconvex<\/strong><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Pack sizes<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The source states that Sinuend is presented in:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>White HDPE securitainers containing 20 tablets<\/strong><\/li>\n\n\n\n<li><strong>Aluminium foil blister packs containing 20 tablets<\/strong><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Practical FAQs (based ONLY on the source)<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Can I take Sinuend if I have high blood pressure?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">No. The source lists <strong>hypertension<\/strong> as a condition where this medicine should <strong>not<\/strong> be used.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Can I give it to a child under 8 years old?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">No. The source says it is <strong>not recommended for children under 8 years<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Can I drive after taking it?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">You should be careful. This medicine may cause <strong>drowsiness and impaired concentration<\/strong>, and the source warns against driving, operating machinery, or climbing dangerous heights if affected.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Can I drink alcohol while taking this?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The source warns that <strong>alcohol can worsen drowsiness and impaired concentration<\/strong> caused by this medicine.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Can I use it for more than a few days?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Not without checking first. The source says <strong>do not use continuously for longer than 10 days<\/strong> unless you have spoken to your doctor.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What should I do if the medicine is not helping?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">If you do not get relief at the recommended dose, the source says you should <strong>consult your doctor<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Is it safe in pregnancy or while breastfeeding?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The source says the <strong>safe use in pregnancy and lactation has not been established<\/strong>. Speak to your doctor or pharmacist before using it.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What if I accidentally take too much?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Get medical help <strong>immediately<\/strong>. The source says to contact a doctor or go to the <strong>nearest hospital at once<\/strong>, because specialised treatment is essential.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Does it contain lactose?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Yes. The source specifically states that it <strong>contains lactose<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Can older people use it?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The source does not say that older adults cannot use it, but it does say they are <strong>more susceptible<\/strong> to some effects of chlorpheniramine, including sedation, low blood pressure, and antimuscarinic effects. Extra caution is therefore important.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>If you are using Sinuend tablets, this medicine is meant to help with the symptoms that often come with a cold or flu. It is used for blocked nose (nasal congestion) as well as minor aches and pains linked to colds and influenza. In South Africa, it is listed as a Schedule 2 (S2) medicine. &#8230; <a title=\"Sinuend tablets in South Africa: Uses, Dosage, Side Effects\" class=\"read-more\" href=\"https:\/\/rxzest.com\/en-za\/sinuend-tablets-africa-dosage-side-effects\/\" aria-label=\"Read more about Sinuend tablets in South Africa: Uses, Dosage, Side Effects\">Read more<\/a><\/p>\n","protected":false},"author":2,"featured_media":955,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[29],"tags":[],"class_list":["post-951","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cold-flu-allergy"],"_links":{"self":[{"href":"https:\/\/rxzest.com\/en-za\/wp-json\/wp\/v2\/posts\/951","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/rxzest.com\/en-za\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/rxzest.com\/en-za\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/rxzest.com\/en-za\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/rxzest.com\/en-za\/wp-json\/wp\/v2\/comments?post=951"}],"version-history":[{"count":3,"href":"https:\/\/rxzest.com\/en-za\/wp-json\/wp\/v2\/posts\/951\/revisions"}],"predecessor-version":[{"id":1261,"href":"https:\/\/rxzest.com\/en-za\/wp-json\/wp\/v2\/posts\/951\/revisions\/1261"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/rxzest.com\/en-za\/wp-json\/wp\/v2\/media\/955"}],"wp:attachment":[{"href":"https:\/\/rxzest.com\/en-za\/wp-json\/wp\/v2\/media?parent=951"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/rxzest.com\/en-za\/wp-json\/wp\/v2\/categories?post=951"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/rxzest.com\/en-za\/wp-json\/wp\/v2\/tags?post=951"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}